Often involved in the pathophysiology of many diseases and complex disorders, including Alzheimer’s, cancer, and inflammation, the causes of which are frequently attributed to oxidative stress, there is a dysregulation observed in the levels of a certain redox-sensitive signaling protein, thioredoxin interacting protein (Txnip), that further triggers or aggravates the diseased state [90]. The gene discussed is TXNIP; the disease is cancer.