Using molecular docking simulation and an in silico absorption, distribution, metabolism, excretion, and toxicity (ADMET) approach, Spriha et al. [42] in their recent investigation aimed to identify some selected agents isolated from the multipotent plant Bergenia ciliate able to inhibit molecular targets involved in breast cancer, including PR (progesterone receptor), ER-α (estrogen receptor-α), EGFR (epidermal growth factor receptor), and HER2 (human epidermal growth factor receptor 2). This evidence concerns the gene ESR1 and breast cancer.