TXNIP and chronic rhinosinusitis with nasal polyps: It was recently reported that thioredoxin (TRX)-interacting protein (TXNIP) may have a negative association with TRX, and the decreased SOD activities and increased malondialdehyde levels resulting in the upregulation of ROS and oxidative stress in nasal epithelial cells may play a pivotal role in the pathogenesis of CRSwNP [40].