In fact, many interventions that have been tested in preclinical models of AKI (e.g., α-MSH, EPO, IL-10, and NGAL) are potent inducers of HO-1 and mediate their effects, at least in part, through HO-1 induction [36,37,38,39,40]. The gene discussed is STAMBP; the disease is acute kidney injury.