RPRD1B and polycystic ovary syndrome: Treatment with clomiphene (68.14 ± 0.92 pg/mL), KH (68.41 ± 0.45 pg/mL), combined KH + metformin (67.99 ± 0.43 pg/mL), or combined KH + clomiphene (68.75 ± 1.36 pg/mL) did not reduce the insulin levels compared with the untreated PCOS rats (71.60 ± 0.49 pg/mL).