This reduction was significantly reversed (p < 0.05) by treatment with KH + metformin (3.43 ± 0.04 U/mg prot), KH + Clomiphene (3.17 ± 0.05 U/mg prot), and KH alone (3.09 ± 0.03 U/mg prot), whereas treatment with metformin (2.12 ± 0.03 U/mg prot) or clomiphene alone (2.06 ± 0.03 U/mg prot) did not increase the catalase activity compared with the untreated PCOS rats. Here, CAT is linked to polycystic ovary syndrome.