However, the use of single IDR1002, indolicidin, Bac2A, CP10A, or IL-2 alone as antimicrobial drugs is usually insufficient to achieve strong and persistent immunity in animals because of their rapid degradation and low bioactivity in vivo; therefore there is an urgent need to develop novel safe and effective immunopotentiator to improve animal resistance against various infectious diseases. The gene discussed is IL2; the disease is infectious disease.