IL6 and periodontitis: Recently, in an in vitro experiment, Porphyromonas gingivalis (Pg) was found to infect dendritic cells (DCs), activate related SASPs (e.g., IL-1β, IL-6, IL-8) and exosomes (EXO), and induce DCs senescence, while affecting surrounding DCs through secreted SASPs and EXO, expanding the senescence range and affecting periodontitis [69].