The present data are in line with those showing that: (i) high reelin expression in the early stages of cancer and a correlation between low reelin expression and more advanced stages of gastric, lung, breast, glioblastoma, neuroblastoma and glioma cancers [32,33,34,35,36], though increased reelin expression was observed in higher grades of prostate cancer [37], and (ii) high reelin expression in areas adjacent to breast cancer [38] and glioblastoma [39]. Here, RELN is linked to glioblastoma.