Among the most activated regulators, l-asparaginase, nelfinavir, calcitriol, OSM, PRKCD, KDM5B, arsenic trioxide, beta-carotene, WT1, TEAD4, vorinostat, slirasib, tanespimycin, and sirolimus can treat cancers by their antineoplastic activity, prevention of metastasis, and suppression of tumour cells (IPK database) suggesting that PFA has considerably similar clinically significant anticancer properties. Here, KDM5B is linked to cancer.