However, the principal objective of this study was not only to reveal the possibility of the cross-hydrolysis of histones, MBP, and DNA by IgGs against these proteins and DNA but, first of all, to find out, using MS patients’ Abs, whether there is an enzymatic cross-activity of Abs against each of the individuals to the four other histones, MBP, and DNA. The gene discussed is MBP; the disease is myeloid sarcoma.