In addition to LAG-3 expression, tumor grading (HR 2.583; 95% CI 1.591–4.192; p < 0.001) and tumor size (HR 1.626; 95% CI 1.020–2.591; p = 0.041) were also identified as independent prognostic factors in the multivariate Cox regression analysis (Table 2, Figure S1). This evidence concerns the gene LAG3 and neoplasm.