ADCYAP1 and neuroblastoma: As widely reported in the literature [41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76], PACAP can act as reducing cell death in different neuroblastoma cell lines, such as SH-SY5Y, when treated with different neurotoxins preserving membrane cells and mitochondrial activity [78].