Moreover, the potent anti-inflammatory cytokine IL-10 followed the same pattern: mean concentrations in severe and critical COVID-19 patients were the lowest, mostly below 50 pg/mL; in patients with sepsis, the mean IL-10 concentration was just below 400 pg/mL; and in CRS patients, it was highest at nearly 800 pg/mL. The gene discussed is IL10; the disease is COVID-19.