ZSWIM1 and neoplasm: For example, the important clinical and pathobiological significance of the ZSWIM1 gene (SWIM-type zinc finger protein 1) was shown in uterine endometrial carcinoma: the expression of this gene in the tumor was lower than in normal tissue, but the high expression of this gene negatively correlated with overall survival; the ZSWIM1 methylation level was downregulated in cancer [61].