PDLIM7 and myeloid sarcoma: In tissue specimens each containing white matter lesions (n = 23), EBV was examined by ISH - all were negative for the EBV transcript EBER. Subset of cases further examined with IHC for expression of EBV latent proteins and found to be negative for LMP1 and EBNA2.RT-PCR was used to detect genomic EBV or EBER1. Neither detected from 17 snap frozen specimens from 5 MS cases.All examined tissue specimens had CD20+ B cells detected.