In particular, most of the amplified genes are involved in proliferation and tumour progression in PDAC, such as AURKA, HRH3, MIR646, MRGBP, PCK1, PMEPA1, SLCO4A1-AS1, SOX18, and TNFRSF6B. The gene discussed is TNFRSF6B; the disease is neoplasm.