In addition to well-known cardiometabolic health markers, such as systolic blood pressure (SBP), diastolic blood pressure (DBP), circulating cholesterol levels, triglycerides (TG), fasting blood glucose (FBG), and body mass index (BMI) [6], recent investigations have demonstrated that circulatory C-reactive protein (CRP) [7,8,9] and adiponectin (APN) [10,11,12,13] are strong predictors of most prevalent cardiometabolic diseases, including metabolic syndrome (MetS), diabetes, hypertension, coronary heart disease, and atherosclerosis. The gene discussed is CRP; the disease is metabolic syndrome.