SREBF1 and steatosis: In the liver, patients with NASH had higher palmitoleic acid (C16:1n-7) levels, a lower stearic acid (C18:0)/palmitic acid (C16:0) ratio (weight/weight), and a higher palmitoleic acid (C16:1n-7)/palmitic acid (C16:0) ratio (weight/weight), higher oleic acid (C18:1n-9)/stearic acid (C18:0) ratio (weight/weight), and higher n-6/n-3 ratio (weight/weight), as well as higher expression of fatty acid metabolism-related genes, including SCD1, ELOVL6, SREBP1, FAS, and PPARγ, than patients with simple steatosis [15].