With regard to PCOS, in a very recent study including 40 women with PCOS and the same number of control individuals, the C allele of SNP C677T in the vaspin gene was reported to increase the risk of PCOS 2.077 times (p < 0.05), and thus was suggested to be a genetic susceptibility marker for PCOS [180]. The gene discussed is SERPINA12; the disease is polycystic ovary syndrome.