The elevation of chemerin levels in FF by ovarian hyperandrogenism of PCOS patients was also shown in a study reporting the correlation of theca cell androgens with increased levels of chemerin and other adipokines in FF, suggesting the existence of a close relationship between these two hormonal systems, which appear deeply involved in ovarian physiology and PCOS physiopathology [143]. The gene discussed is RARRES2; the disease is Ovarian Hyperandrogenism.