Moreover, a two-center retrospective study of 288 consecutive patients with IIP showed that anti-Ro52 (20/288; 6.9%), anti-ARS (18/288; 6.3%), and anti-Ro60 (16/288; 5.6%) were the most common autoantibodies detected, and that anti-ARS antibodies were present in 8 (40%) of 20 IIP patients with anti-Ro52 antibodies [20]. Here, TRIM21 is linked to idiopathic interstitial pneumonia.