The thalidomide analog-mediated degradation of SALL4 in human Tera-1 cells (0.01, 0.1, 1 μM of pomalidomide and F-3,6′-DP) and of Aiolos and Ikaros in the human multiple myeloma MM1.S cell line (1 μM of pomalidomide and of F-3,6′-DP) was evaluated by Western blotting with quantification relative to GAPDH expression. Here, SALL4 is linked to AL amyloidosis.