ADAMTS15 and Arthritis: In addition, ADAMTS15 is involved in the turnover of cartilage and/or bone during joint inflammation [120] and the inverse correlation of ADAMTS15 and CITED2 (Cbp/P300 Interacting Transactivator With Glu/Asp Rich Carboxy-Terminal Domain 2) expression links it to the Wnt pathways associated with bone formation and inflammatory arthritis [120].