SERPINE1 and keratoconus: Of these, 3 appeared over-expressed in the isolated exosomes of corneal stroma cells from patients with KC compared to healthy individuals (ACTB, SERPINE1, HGFAC), while 7 were under-expressed (HRNR, CTNNB1, DSG1, GSN, LTF, GNAS, SERPINB3).