In addition, the second tumor suppressor MIR99AHG/miR-218-5p/GPM6A axis provides two-fold lung cancer inhibition via non-coding tumor suppressor gene MIR99AHG in lung adenocarcinoma [41] and miR-218-5p affects lung adenocarcinoma progression [42]. The gene discussed is GPM6A; the disease is lung adenocarcinoma.