LAMC2 and familial pancreatic carcinoma: In vitro, we confirmed the absence of LAMC2 expression (gene and protein) in Normal Pancreatic cancer cells (i.e., HPNE [36] compared to two established pancreatic cancer cell lines (L3.6pl and PANC-1) and two human PDAC-derived primary cultures (#215 and #253) [4, 37] (Fig. 1h and Fig. 1i).