Additionally, in the subgroup analysis, the TyG index had interaction effects with age (P value for interaction = 0.043), BMI (P value for interaction < 0.001), HDL-C (P value for interaction < 0.001), and AST/ALT (P for interaction = 0.011) on NAFLD risk after adjusting for potential confounders (Model 4). This evidence concerns the gene GPT and metabolic dysfunction-associated steatotic liver disease.