The top 10 mutated genes were FLG, MUC17, MUC5B, RP1L1, NBPF1, GOLGA6L2, SLC29A3, SGK223, PTGFRN, and FAM186A. Among the prevalent mutated genes, 7 variants in exons with changes in protein coding are important for the development of mature cystic teratomas of the ovary, including PTGFRN, DUSP5, MPP2, PHLDA1, PRR21, GOLGA6L2, and KRTAP4-2. This evidence concerns the gene DUSP5 and ovarian cystic teratoma.