However, when all these variables were fitted into a multivariable logistic regression model, younger age, higher perioperative BMI, shorter duration of T2DM, no insulin therapy, lower preoperative FBS and HbA1c, and not having a family history of obesity were significantly associated with increased the probability of diabetes remission at 1-year and 3 years after surgery (p < 0.05). The gene discussed is INS; the disease is diabetes mellitus.