In both iBEC-LMC and iBEC monocultures, CXCL8, CXCL1, CXCL2, and CCL20 were upregulated during the time course of infection, with higher upregulation of CXCL8 and CXCL1 in the monoculture model at 24 h p.i. (Fig. 5a). The gene discussed is CXCL8; the disease is infection.