Specifically, patients with severe COVID-19 and high body mass indices tend to have increased IL-6 levels, endothelial injury, IFN activation, and cytokine profiles (e.g., IFN-γ, IL15, IL17, MCP1/CCL2, MIP1-beta/CCL4) that suggest macrophage recruitment [51]. This evidence concerns the gene IFNA1 and COVID-19.