Although endothelial cells express ACE2 and TMPRSS2 and, thus, are potentially infected by SARS-CoV-2, most data suggest that endothelial damage in the context of COVID-19 results from immune activation of endothelial cells by cytokines, kallikrein-kinin activation, IL-6 induction, and complement activation [79]. Here, IL6 is linked to COVID-19.