Three patients showed concordantly positive PD-L1 results (In two of these patients PD-L1 status was determined in the primary breast tumor and a skin metastasis and in one patient in the primary breast tumor and a supraclavicular lymph node metastasis, respectively), while one patient had a PD-L1 positive axillary lymph node metastasis and a PD-L1 negative brain metastasis. Here, CD274 is linked to metastatic malignant neoplasm in the lymph nodes.