The lowest EC50 values, obtained for As4S4/ZnS/Fe3O4 (1:4:1) with FA and Alb, were on average threefold higher in healthy MNCs than in non-PCs and on average 19-fold higher than the CD138+ PC population in MM patients, suggesting a rationale for composite NPs clinical evaluation in MM. Here, ALB is linked to Miyoshi myopathy.