BRWD1 and Anxiety: We generated herpes simplex virus (HSV) vectors to overexpress BRWD1 (HSV-BRWD1-GFP) vs. an empty vector control (HSV-GFP) in adult male dorsal hippocampus (CA1), followed by a battery of behavioral assays to assess the impact of Brwd1 overexpression on context- and spatial-dependent learning and memory, as well as anxiety and anhedonia related behaviors.