Notably, we found that the mTOR pathway was significantly enriched in the autophagy score-low group in three cancers (LUSC: false discovery rate [FDR] = 0.032; SARC: FDR = 0.004, thyroid carcinoma (THCA): FDR = 0.009; Fig. 3b), which was consistent with previous observations that the mTOR pathway inhibits autophagy1. This evidence concerns the gene MTOR and cancer.