Indeed, analysis of both peripheral blood and spleens on day 14 after tumor resection and implantation showed significantly elevated proportions of (CD44+CD62L+) CD8+ central memory T cells among total CD8+ T cell population in the FLICs-loaded hydrogel implants (with FRL) group compared to controls (Fig. 6b, c). The gene discussed is CD44; the disease is neoplasm.