MSH6 and hepatocellular carcinoma: For example, MSH2 is positively correlated with oncogene expression [27], mismatch repair Repair-related gene EXO1 plays an oncogenic role in HCC [28], MSH6 is an up-regulated HCC staging-related gene, and high expression of MSH6 is positively correlated with 1-year recurrence of HCC [29], which is consistent with our results.