NFE2L2 and fatty liver disease: Ye et al. reported that BPs from monkfish muscle could mitigate high fat diet-induced hepatic steatosis in mice through up-regulating the content of phospho-AMP-activated protein kinase (p-AMPK), which further activate the nuclear factor erythroid-2-related factor 2 (Nrf2) pathway to increase the levels of heme oxygenase-1 (HO-1) and nicotinamide quinone oxidoreductase 1 (NQO1) [29].