In this scenario, we considered two molecular targets in this study, viz., caspase-1 and cathepsin B, which are applicable to several brain diseases involving inflammatory effect, but important targets for Alzheimer’s disease (AD), considering that, in the pathology, both enzymes are activated by amyloid peptides and cause effects on neurodegeneration [21]. Here, CTSB is linked to early-onset autosomal dominant Alzheimer disease.