The keywords used in the literature search were “Ecklonia stolonifera” or “Bioactive” or “Compound” or “bioactivity,” “Antibacterial” or “Tyrosinase inhibition” or “Antioxidant” or “Anti-obesity” or “Anti-diabetic” or “Anti-inflammatory” or “Treat neurological disorders” or “anti-photoaging” or “antisenescence” or “phlorotannin”. This evidence concerns the gene TYR and obesity due to melanocortin 4 receptor deficiency.