We did not find any significant differences between groups regarding heart failure-related clinical features, such as etiology of heart failure, New York Heart Association (NYHA) functional class, N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) levels, left ventricular ejection fraction (LVEF), pulmonary artery systolic pressure (PASP), or mitral regurgitation severity on echocardiography. This evidence concerns the gene NPPB and mitral valve insufficiency.