Significant differences were noted in sex, age, smoking history, hypertension history, heart failure, HbA1c, GLU, BMI, HR, AST, APOA, LDH, MYO, SCR, β2 microglobulin (β2MG), E/e’ and CTRP9 (p < 0.050) among the four groups. The gene discussed is APOA1; the disease is heart failure.