ADAM17 and neoplasm: In patients with concomitant CVD, a statistically significantly higher protein concentration of ADAM17 in the margin tissue was demonstrated (0.21 vs. 0.13 ng/μg protein, p < 0.01); in the tumor, the protein concentration was also higher, but the necessary statistical significance point was not reached (0.25 vs. 0.19 ng/μg protein, p = 0.05).