For example, we previously reported that a protein (circFNDC3B‐218aa) encoded by circFNDC3B could inhibit colon cancer progression though the Snai1/FBP1 pathway, suggesting that circFNDC3B‐218aa performed its biological function independently.[47] On the other hand, some products encoded by circRNAs reciprocally affect their host gene. This evidence concerns the gene FBP1 and malignant colon neoplasm.