Immunofluorescent, Western Blot, and qPCR showed that C8018‐7840 notably decreased CCL18‐PITPNM3 induced vimentin and recovered CDH1 expression (Figure 4B,E; Figure S11D,E, Supporting Information), which further confirmed that C8018‐7840 inhibited PITPNM3 dependent tumor metastasis. This evidence concerns the gene PITPNM3 and neoplasm.