Since MGP and TRPS1 showed high expression in luminal A/B, HER2-enriched, TNBC/basal-like, and normal-like subtypes according to the PAM50 subtyping (Fig. 3, Additional file 1: Figure S1), we selected MGP, TRPS1, and GATA3 for further validation in 1201 cases of breast carcinoma of different subtypes and normal breast tissues. This evidence concerns the gene MGP and breast carcinoma.