The close alignment of neuroradiological features between the tubulinopathies, PAFAH1B1(LIS1)-related lissencephaly, and the CAMSAP1-related neuronal migration disorder is consistent with a shared pathomolecular mechanism underlying these diseases and highlights the role of the minus end of the microtubule in neuronal migration disorders. This evidence concerns the gene PAFAH1B1 and Abnormality of neuronal migration.