AKT1 and cancer: As shown in Figure 6A, the KEGG enrichment analysis illustrated that signaling genes (top 5% genes with the highest local DNRS) in these cancer datasets were mainly enriched in cancer-related pathways, such as PI3K-Akt signaling pathway, Proteoglycans in cancer, FoxO signaling pathway, MAPK signaling pathway, and Wnt signaling pathway.