For example, 35 out of 46 collagen genes exhibited changes in at least one comparison (Bakay EDMD, G1 or one of the subgroups gp1, gp2 and gp3) and all patients had multiple of these genes altered (Supplementary Material, Fig. S5). This evidence concerns the gene GTPBP1 and Emery-Dreifuss muscular dystrophy.