Increased transcripts of IFI27 within VA and slightly less in noVA tissues, also reported in rheumatoid arthritis (RA), psoriasis [82, 83], and UC [84], were especially observed in NV+ tissue samples and probably reflect a mixed response of IFN type I/III in an IFN-γ/TNF-α-enriched environment [83]. The gene discussed is IFI27; the disease is psoriasis.