ScRNA-seq in non-myocyte Pdgfra positive cells at days 3 and 7 post myocardial infarction (MI) identified novel fibroblast cell states, including a population characterized by the expression of canonical WNT pathway inhibitors along with several stress-activated fibroblasts subtypes with pro- or anti-fibrotic signatures [24]. The gene discussed is PDGFRA; the disease is myocardial infarction.